Abstract:
Six hundred and seventy seven animals belonging to 13 spp of reptile and amphibian namely Agama agama (African lizard0),Anolis carlinensis (green lizard) Hyyla ()green tree frog),etc were investigated for isolation of Basidiobolus spp. the fungus was recovered from the intestinal content of nin of the animal spp.Some of the eg americanus and terrestris have not been known before to habour the fungus in their intestinal contents. Ultrastructural effect of ketoconazole on an isolated of B haptosporus confirmed detioration of subcellular. organelles which let tocellnecrosis. Amphotericin B and septrin were also found to have significant in vitro antifungal activity.